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The following represent a comprehensive list of articles that address the use of Acyclovir tablets as an effective genital herpes treatment:

Short Course of Acyclovir for Genital Herpes
European Family Physician
August, 2007

Treatment of Recurrent Genital Herpes Infections
European Family Physician
July,
2007

Treatment of Genital Herpes
European Family Physician
September, 200
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Short Course of Acyclovir for Genital Herpes
European Family Physician
August, 2007

Patients with recurrent genital herpes will definitely experiment with shorter courses of antiviral medication as they gain experience with the disease. Studies of viral replication have shown that active viral reproduction ends in the first few days of recurrent infections, well before the resolution of genital lesions or clinical symptoms. Wald and associates conducted a randomized, double-blind, placebo-controlled trial of higher-dose, shorter-course Acyclovir in the treatment of recurrent genital herpes.

The study enrolled patients with recurrent genital herpes (i.e., at least three documented outbreaks in the year before the study). Patients were randomized to treatment with either acyclovir at 800 mg or placebo (sugar pill), three times daily for two days.

Acyclovir was more than three as likely as placebo to completely abort recurrence of the genital herpes virus infection. In patients who developed active lesions, viral shedding was reduced by more than one half with acyclovir and the duration of skin ulcers also decreased.

Acyclovir, effective genital herpes treatment. Decrease the number of genital herpes outbreaks, the severity of the ulcers and viral shedding with Acyclovir tablets (click here for details).

These results were comparable with results published elsewhere for standard antiviral regimens. There was no significant difference in the likelihood of a subsequent herpes outbreak with the shorter-course regimen. The higher-dose, shorter-course regimen of acyclovir (800 mg three times daily for two days) promoted better compliance than standard dosing (200 mg five times daily for five days) but had the same overall cost because the total drug dosage was similar.

The authors conclude that a shorter course of higher-dose acyclovir for recurrent genital herpes is effective in aborting recurrences, decreasing viral shedding, and speeding clinical resolution of outbreaks.

Acyclovir, effective genital herpes treatment. Decrease the number of genital herpes outbreaks, the severity of the ulcers and viral shedding with Acyclovir tablets (click here for details).

BILL ZEPF, M.D.
Wald A, et al. Two-day regimen of acyclovir for treatment
of recurrent genital herpes simplex virus type 2 infection.

 

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Treatment of Recurrent Genital Herpes Infections
European Family Physician
July, 1998

Acyclovir has been widely used as an effective and well-tolerated drug for the treatment of recurrent genital herpes simplex virus infection. Early initiation of treatment has been shown to reduce duration of viral shedding, time until healing and time until clearance of ulcers.

Buy Acyclovir tablets, effective genital herpes treatment. Decrease the number of genital herpes outbreaks, the severity of the ulcers and viral shedding with Acyclovir tablets (click here for details).

The double-blind, randomized study included 1,200 patients with recurrent genital herpes. Study subjects underwent therapy with oral Acyclovir, 1,000 mg twice daily; oral acyclovir, 200 mg five times daily, or placebo.

Acyclovir significantly decreased the length of the genital herpes episode compared with placebo (sugar pill). Acyclovir significantly reduced the time until lesion healing compared with placebo. At least one culture for herpes simplex virus was obtained from approximately 90 percent of the patients in each treatment group. Culture results were negative in 49 percent of the active Acyclovir groups, compared with 10percent in the placebo group. The duration of viral shedding was significantly longer in the placebo group.

In addition, Acyclovir significantly decreased the duration of pain compared with placebo. .

Acyclovir Genital Herpes Treatment Conclusion

The authors conclude that treatment of recurrent herpes infections with a twice-daily regimen of of acyclovir is significantly more effective than placebo in decreasing pain, and shortening the overall length of an episode and the period of viral shedding.

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Treatment of Genital Herpes
European Family Physician
September, 2007

In Europe, an estimated 21 percent of persons 17 years and older are infected with herpes simplex virus. The prevalence has increased by 30 percent in the past 15 years. Many patients with the genital herpes virus are asymptomatic, and an estimated 80 percent of cases are never diagnosed. Both overt and suspected cases should be confirmed by viral culture because of the long-term nature of the condition and its potentially serious physical and psychologic effects.

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Choice of treatment should be individualized, but the main treatment strategies are episodic or suppressive therapy. The primary infection should be vigorously treated with oral agents such as Acyclovir,  Topical treatment alone is less effective than oral treatments, such as, Acyclovir. Episodic therapy requires aggressive treatment of recurrences with these Acyclovir. Suppressive therapy generally uses lower doses of acyclovir, on a daily basis.

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