Information About Levitra
(latest Levitra news, Levitra proven impotence treatment)
Levitra is a new class of medication to help
men with erectile dysfunction. Viagra was the first of the so called, "PDE-5
inhibitors" and Levitra is known in the same class to significantly help men
enhance their erections. Similar to Viagra, Levitra increases the blood flow to
the penis thus improving the erection. Levitra is very selective in inhibiting
the PDE-5 without affecting other isoenzymes. This allows a smaller dose of
Levitra to have a more pronounced effect as a
larger dose of Viagra (the standard dose of
Levitra dose is 10mg while the standard dose of
Viagra dose is 50mg). Through this action, smooth muscle in the penis remains
relaxed for a longer period. This allows for increased blood flow into the
cavernous tissue of the penis thereby generating a stronger, firmer erection.
Levitra The Facts:
- Levitra produced enhanced erections (enhanced
rates of penetration and hardness) in some ninety percent of men.
- Levitra can begin enhancing your erection 16-30
minutes prior to intercourse.
- Clinical studies have shown that Levitra is
extremely effective in treating erectile dysfunction following prostate
cancer surgery.
- Clinical studies have also shown that Levitra
as proven to be effective in many men who did not have positive results
using Viagra.
Order one of the newest erectile enhancement medications.
Your Levitra order will be discreetly shipped to you with no hint
of the contents (click here for details)
More Information About Levitra
The following Levitra information has been compiled from a variety
of resources in order to give you details concerning the use of Levitra
in enhancing erections:
How effective is
Levitra
in treating impotence and enhancing erections?
Recent reports release by Bayer the manufacturer of Levitra report
some ninety percent of men taking
Levitra reported enhanced erections. In
addition,
Levitra consistently improved rates of
penetration and hardness of the erection, as well as, success with
intercourse in a broad population of men with erectile dysfunction
(impotence).
Buy Levitra securely online (click here for details)
How much does Levitra cost?
The following represent discount online Levitra prices for both Levitra
20mg pills and Levitra 10mg pills:
Review Our Discounted Levitra
Prices
|
Discount Levitra
20mg
Prices
|
|
Medication
|
Quantity
|
Consultation
|
Shipping
|
Sale Price
|
Buy Levitra
Online
|
|
Levitra 20mg
|
4 Levitra
|
FREE
|
FREE
|
£73.00
|
|
|
Levitra 20mg
|
8 Levitra
|
FREE
|
FREE
|
£125.00
|
|
|
Levitra 20mg
|
12 Levitra
|
FREE
|
FREE
|
£169.00
|
|
|
Levitra 20mg
|
16 Levitra
|
FREE
|
FREE
|
£199.00
|
|
|
Most
Popular!Levitra
20mg
|
24 Levitra
|
FREE
|
FREE
|
£279.00
|
|
|
Levitra 20mg
|
32 Levitra
|
FREE
|
FREE
|
£339.00
|
|
|
Best
Deal!
*Levitra
20mg
|
64
Levitra
|
FREE
|
FREE
|
£635.00
|
|
*Good News,
buy larger quantities of Levitra and save even
more. You can save an additional 15-20 percent
per Levitra pill when buying larger quantities
of Levitra.
Buy 24 or
more Levitra, with the discount is like getting
a free Levitra pill for every five Levitra you
purchase.
|
 Bayer
Pharmaceuticals make the genuine Levitra
2.5mg, 5mg, 10mg, and 20mg doses.
However, some doctors are not cost conscious and write
prescriptions for the standard dose, Levitra 10mg tablets.
Our doctors give you the option to order Levitra 20mg
tablets and then split the Levitra 20mg tablets into two
Levitra 10mg doses for a substantial savings.
|
Discount Levitra
10mg
Prices
|
|
Medication
|
Quantity
|
Consultation
|
Shipping
|
Sale Price
|
Buy Levitra
Online
|
|
Levitra 10mg
|
4 Levitra
|
FREE
|
FREE
|
£73.00
|
|
|
Levitra 10mg
|
8 Levitra
|
FREE
|
FREE
|
£125.00
|
|
|
Levitra 20mg
|
12 Levitra
|
FREE
|
FREE
|
£169.00
|
|
|
Levitra 10mg
|
16 Levitra
|
FREE
|
FREE
|
£199.00
|
|
|
Most
Popular!Levitra
10mg
|
24 Levitra
|
FREE
|
FREE
|
£279.00
|
|
|
Levitra 10mg
|
32 Levitra
|
FREE
|
FREE
|
£339.00
|
|
|
Best
Deal!
*Levitra
10mg
|
64
Levitra
|
FREE
|
FREE
|
£635.00
|
|
*Good News,
buy larger quantities of Levitra and save even
more. You can save an additional 15-20 percent
per Levitra pill when buying larger quantities
of Levitra.
Buy 24 or
more Levitra, with the discount is like getting
a free Levitra pill for every five Levitra you
purchase.
|
|
|
Why is
Levitra
sometimes called Vardenafil HCL?
Levitra is the brand name and Vardenafil HCL is the generic name for the
medication.
Buy Levitra Vardenafil HCL securely online (click here for details).
How good is
Levitra
as compared to
Viagra in treating erectile dysfunction
(impotence)?
Many men in clinical studies have reported that Levitra lasts longer,
produces an erection faster, has fewer side effects, and helps more men
achieve fuller erections when compared to
Viagra.
More clinical studies need to be completed to evaluate the two
medications for treating impotence. Levitra is the new alternative to
Viagra!
Enhance your erections buy Levitra securely online (click here for details).
How long prior to intercourse does an
individual need to take Levitra?
Some reports suggest that
Levitra will begin to exert the
medication's action in as quickly as sixteen minutes and may work for up
to twenty four hours enabling a man to have improved erections. Once a
man reaches climax, his erection will decrease in the normal fashion,
however, Levitra will in most cases allow the man to develop a second
erection in less time.
Enhance your erections buy Levitra securely online (click here for details).
What is the appropriate dose of
Levitra?
Currently, Levitra is available in 2.5mg, 5mg, 10mg, and 20mg doses. The
standard dose is to take an initial dose of 10mg. This dose is decreased
for various medical conditions (liver conditions, end stage renal
disease, hypo tension, cardiovascular disease, taking other medications,
etc.) and increased up to 20mg if the standard dose is not effective in
healthy individuals. Men over the age of 65 years will often take a
lower dose. Similar to any prescription medication, consult with a
physician prior to taking Levitra.
Enhance your erections buy Levitra securely online (click here for details).
Similar to Viagra can individuals buy a larger
dose of Levitra and then split the dose?
Yes, you can buy the 20mg Levitra tablets and then split the dose into
the standard dose of 10mg. Some individuals split the 20mg tablets into
fourths and just take 5mg of Levitra. You should not take more than 20mg
of Levitra during any given 24 hour period.
Enhance your erections buy Levitra securely online (click here for details).
Which pharmaceutical company manufactures
Levitra?
Levitra is manufactured by the Bayer corporation in Germany and will
subsequently be distributed and marketed by GlaxoSmithKline.
Buy genuine Bayer Levitra securely online (click here for details).
Is Levitra an effective treatment option for
erectile dysfunction following prostate surgery?
Levitra is extremely effective in treating erectile dysfunction
(impotence) following prostate cancer surgery. Some 81% of men who had
undergone prostate removal reported significant improvements in
erections with Levrita (20mg) versus 12 per cent in men taking placebo
(sugar pill).
The study concluded that this was an important
finding for Levitra, as erectile dysfunction (impotence) following
prostate surgery is usually common.
Enhance your erections buy Levitra securely online (click here for details).
What is the mechanism of action of
Levitra?
Levitra is a new class of medication to help men with erectile
dysfunction (impotence). Viagra was the first of the so called, "PDE-5
inhibitors" and Levitra is known in the same class to significantly help
individuals treat their erectile dysfunction (impotence). Similar to
Viagra, Levitra increases the quantity of blood supplied to the penis
thus improving the erection. Levitra is very selective in inhibiting the
PDE-5 without affecting other isoenzymes. This allows a smaller dose of
Levitra to have a more pronounced effect as a larger dose of Viagra (the
standard dose of Levitra dose is 10mg while the standard dose of Viagra
dose is 50mg). Through this action, smooth muscle in the penis remains
relaxed for a longer period. This allows for increased blood flow into
the cavernous tissue of the penis thereby generating an erection.
Levitra is unique in that it increases a natural occurring process,
therefore, only through sexual stimulation will an erection occur.
More specifically, Penile erection is a
haemodynamic process. During sexual stimulation, nitric oxide is
subsequently released. The nitric acid activates an enzyme guanylate
cyclase, resulting in an increased level of cyclic guanosine
monophosphate (cGMP) in the corpus cavernosum of the penis. This results
in smooth muscle relaxation in the penis, allowing increased inflow of
blood into the penis. The level of cGMP is regulated by the rate of
synthesis via guanylate cyclase and by the rate of degradation via cGMP
hydrolysing phosphodiesterases (PDEs).
Levitra is a potent and selective
inhibitor of the cGMP specific phosphodiesterase type 5 (PDE5), the most
prominent PDE in the human corpus cavernosum. Levitra enhances the
effect of endogenous nitric oxide in the corpus cavernosum by inhibiting
PDE5. When nitric oxide is released secondary to sexual stimulation,
inhibition of PDE5 by
Levitra results in increased corpus
cavernosum levels of cGMP. Sexual stimulation is required for Levitra to
produce its beneficial therapeutic effects.
Is there a generic version of
Levitra?
Levitra is still under the patent of Bayer/GlaxoSmithKline which have
the exclusive rights to market
Levitra . Some companies may advertise
a generic version of Levitra, however, this medication is not approved
or tested by the FDA or European regulators so you cannot be sure of the
purity and/or quality of the medication.
Does
Levitra
help with erectile dysfunction related
depression?
Yes, studies have shown that Levitra is effective in treating the
depressive symptoms experienced by men with erectile dysfunction
(impotence). These studies showed men taking Levitra reported improved
erections and fewer depressive symptoms than those men taking a placebo
(sugar pill).
Enhance your erections buy Levitra securely online (click here for details).
Are there any drug
interactions associated with the use of Levitra?
Studies in human liver microsomes showed that Levitra is metabolized
primarily by cytochrome P450 (CYP) isoforms 3A4/5, and to a lesser
degree by CYP 2C9. Therefore, inhibitors of these enzymes are expected
to reduce Levitra clearance.
Cytochrome P450
Inhibitors:
- Cimetidine:
(400 mg b.i.d.) had no effect on vardenafil bioavailability (AUC) and
maximum concentration (Cmax) of vardenafil when co-administered with
20 mg LEVITRA in healthy volunteers.
- Ketoconazole:
(200 mg once daily) produced a 10-fold increase in vardenafil AUC and
a 4-fold increase in Cmax when co-administered with Levitra (5 mg)
in healthy volunteers. A 5-mg Levitra dose should not be exceeded
when used in combination with 200 mg once daily ketoconazole. Since
higher doses of ketoconazole (400 mg daily) may result in higher
increases in Cmax and AUC, a single 2.5 mg dose of Levitra should
not be exceeded in a 24-hour period when used in combination with
ketoconazole 400 mg daily.
- Erythromycin:
(500 mg t.i.d) produced a 4-fold increase in vardenafil AUCand a
3-fold increase in Cmax when co-administered with Levitra 5 mg in
healthy volunteers It is recommended not to exceed a single 5 mg
dose of Levitra in a 24-hour period when used in combination with
erythromycin.
HIV Protease Inhibitors:
Ritonavir
and Indinavir: Upon concomitant
administration of 5 mg of Levitra with 600 mg BID ritonavir, the Cmax
and AUC of ritonavir were reduced by approximately 20%. Upon
administration of 10 mg of Levitra with 800 mg TID indinavir , the Cmax
and AUC of indinavir were reduced by 40% and 30%, respectively.
The interaction is a consequence
of blocking hepatic metabolism of vardenafil by ritonavir, a highly
potent CYP3A4 inhibitor, which also inhibits CYP2C9. Ritonavir
significantly prolonged the half-life of vardenafil to 26 hours.
Consequently, it is recommended not to exceed a single 2.5 mg Levitra
dose in a 72-hour period when used in combination with ritonavir.
Additional Drug
Interactions:
Alpha-blockers:
When Levitra 10 or 20 mg was given to healthy volunteers either
simultaneously or 6 hours after a 10 mg dose of Terazosin, significant
hypotension developed in a substantial number of subjects. With
simultaneous dosing of Levitra 10 mg and Terazosin 10 mg, 6 of 8
subjects experienced a standing systolic blood pressure of less than 85
mm Hg. With simultaneous dosing of Levitra 20 mg and terazosin 10 mg, 2
of 9 subjects experienced a standing systolic blood pressure of less
than 85 mm Hg. When Levitra dosing was separated from Terazosin 10 mg by
6 hours, 7 of 28 subjects who received 20 mg of Levitra experienced a
decrease in standing systolic blood pressure below 85 mm Hg. In a
similar study with Tamsulosin in healthy volunteers, 1 of 24 subjects
dosed with Levitra 20 mg and Tamsulosin 0.4 mg separated by 6 hours
experienced a standing systolic blood pressure below 85 mm Hg. Two of 16
subjects dosed simultaneously with Levitra 10 mg and Tamsulosin 0.4 mg
experienced a standing systolic blood pressure below 85 mm Hg.
The administration of lower doses of Levitra with alpha blockers has not
been completely evaluated to determine if they can be safely
administered together. Based on these data, Levitra should not be used
in patients on alpha-blocker therapy.
Nitrates: The
blood pressure lowering effects of sublingual nitrates (0.4 mg) taken 1
and 4 hours after vardenafil and increases in heart rate when taken at
1, 4 and 8 hours were potentiated by a 20 mg dose of Levitra in healthy
middle-aged subjects. These effects were not observed when Levitra 20 mg
was taken 24 hours before the NTG. Potentiation of the hypotensive
effects of nitrates for patients with ischemic heart disease has not
been evaluated, and concomitant use of Levitra and nitrates is
contraindicated.
Nifedipine:
Vardenafil 20 mg, when co-administered with slow-release
Nifedipine 30 mg or 60 mg once daily, did not affect the relative
bioavailability (AUC) or maximum concentration (Cmax) of nifedipine, a
drug that is metabolized via CYP3A4. Nifedipine did not alter the plasma
levels of Levitra when taken in combination. In these patients whose
hypertension was controlled with Nifedipine, Levitra 20 mg produced mean
additional supine systolic/diastolic blood pressure reductions of 6/5 mm
Hg compared to placebo.
Alcohol: Alcohol
(0.5 g/kg body weight: approximately 40 mL of absolute alcohol in a 70
kg person) and vardenafil plasma levels were not altered when dosed
simultaneously. Levitra (20 mg) did not potentiate the hypotensive
effects of alcohol during the 4-hour observation period in healthy
volunteers when administered with alcohol (0.5 g/kg body weight).
Aspirin: Levitra
(10 mg and 20 mg) did not potentate the increase in bleeding time caused
by aspirin (two 81 mg tablets).
Other interactions:
Levitra had no effect on the pharmacodynamics of Glyburide (glucose and
insulin concentrations) and warfarin (prothrombin time or other
pharmacodynamic parameters).
In addition, no pharmacokinetic
interactions were observed between Vardenafil and the following drugs:
Maalox, Glyburide, Warfarin, Digoxin, and Ranitidine. In the Warfarin
study, Vardenafil had no effect on the Prothrombin time or other
pharmacodynamic parameters.
Why should Levitra not be used if an individual
is taking Nitrates?
Individuals should be counseled that concomitant use of Levitra with
nitrates could cause blood pressure to suddenly drop to an unsafe level,
resulting in dizziness, syncope, or even a stroke or heart attack.
Why should Levitra not be used if an individual
is taking Alpha-blockers?
Physicians should inform their patients that concomitant use of Levitra
with alpha-blockers is contraindicated because co-administration can
produce hypotension that could increase the work load of the heart to
potentially dangerous levels.
back to the top
of the page
Are there individuals that should
not take Levitra?
Yes, there are some patient subgroups that have not been studied in
clinical trials. Therefore, the use of Levitra is not recommended in the
following patients until further studies are completed: or until an
individuals physician has approved the use of the medication:
- Unstable angina
- Severe hepatic impairment
(Child-Pugh C)
- End stage renal disease
requiring dialysis
- Known hereditary degenerative
retinal disorders, including retinitis pigmentosa
- Hypotension (resting systolic
blood pressure of <90 mm Hg)
- Uncontrolled hypertension
(>170/110 mm Hg)
- Recent history of stroke,
life-threatening arrhythmia, or myocardial infarction (within the
last 6 months); severe cardiac failure
- If you have an allergy (if
you're hypersensitive) to vardenafil or any of the other ingredients
of Levitra.
- If you are taking other
medications (consult with your physician)
- Cardiovascular complications
(stroke, arrhythmia, heart attack, etc.)
- Degenerative eye disease i.e.
retinitis pigmentosa
Additional caution should
be used in the following individuals:
- Individuals with a physical
condition affecting the shape of the penis (i.e. angulation,
Peyronie's disease and cavernosal fibrosis, etc.).
- Individuals with an illness
that can cause priapism or sustained erections (i.e. sickle cell
disease, multiple myeloma and leukemia, etc.).
- Individuals that have stomach
ulcers (i.e. gastric or peptic ulcers).
- Individuals with a bleeding
disorder (i.e. haemophilia).
- Individuals that are using any
other treatments for erection difficulties (i.e. Viagra, Cialis).
Will
Levitra
produce an erection for hours?
Levitra only enhances a man's natural ability to achieve an erection
when you are sexually stimulated. Erections should end following an
orgasm or the end of stimulation. In the rare case your erection should
lasts for more than 4 hours, please seek immediate medical attention.
Enhance your erections buy Levitra securely online (click here for details).
Impotence Pills
I Erectile
Dysfunction Treatment I
Impotence Treatment
I
Sexual Health
I
Pharmacy Navigation
