Propecia and baldness, information concerning Propecia and baldness treatment.

 

 

Propecia and Baldness

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The following represents a comprehensive list of articles that address Propecia and baldness. Propecia remains the most recommended baldness (hair loss treatment):

New Five-Year Study with Propecia Showed That the `Hair Count' Gap Grew Over Time Between Men Who Treated Baldness with Propecia, Compared to Men Who Didn't
PR Newswire
March, 2007

Propecia - A Review of Its Use in Male Pattern Baldness
Impotence & Male Health Weekly Plus
February, 2007

As Young as You Feel: Weapons to Combat the Effects of Aging
Men's Fitness
Feb, 2007

Information from Your Family Doctor
American Family Physician
April, 1999

Drug Update: Baldness in Men
Family Practice news
April , 2007

 


New Five-Year Study with Propecia Showed That the `Hair Count' Gap Grew Over Time Between Men Who Treated Hair Loss with Propecia, Compared to Men Who Didn't
PR Newswire
March 15, 2007

The longest controlled clinical trial of baldness treatment ever reported showed that men who took Propecia compared to men who took a placebo (sugar pill) had a considerable difference in their hair counts after five years, according to data presented at the 59th Annual Meeting of the American Academy of Dermatology.

"This study provides new, long-term scientific data that Propecia helped the majority of men with predominantly vertex male pattern baldness keep the amount of hair they have, as well as grow new hair," said Keith Kaufman, M.D., senior director, Clinical Research, Merck Research Laboratories. "The study also was the first controlled clinical trial to evaluate the course of untreated baldness over a five-year period and to show the progressive nature of male pattern baldness."

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Five-year Propecia and Baldness Treatment Efficacy Results

The studies assessed the efficacy of Propecia by four separate endpoints: hair counts in a one-inch diameter circle of the scalp; assessments of "before" and "after" photographs by a panel of dermatologists; patient questionnaires and investigator assessments of changes in scalp hair growth.

The effectiveness of Propecia vs. placebo was demonstrated as follows:

-- Hair count: At the start of the studies, baseline hair counts averaged 876 hairs in a one-inch diameter area of scalp. By the end of the first year, men taking Propecia had an average of 1026 more hairs than men taking placebo (sugar pill). This difference continued to grow, and, by the end of the fifth year, the net difference between the groups increased to 1177 hairs in favor of the men taking Propecia. At the end of the fifth year, 85 percent of men taking Propecia maintained or improved their hair count compared to their hair count at the start of the studies, while all of the men on placebo (sugar pill) lost hair count.

-- Before and after photos: The panel of dermatologists who reviewed standardized clinical photographs of men treated with Propecia  and men on placebo  at the end of the five-year study rated 90 percent of men treated with Propecia as having had no further visible hair loss.

Propecia and Baldness Conclusions

Without a doubt Propecia represents both a valid and effective treatment for baldness (hair loss). Men who take Propecia show no continued hair loss and a significant re growth of hair that had been previously lost.

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Propecia - A Review of Its Use in Male Pattern Baldness
Impotence & Male Health Weekly Plus
February
2007

According to the authors' abstract of an article published in Drugs, "The 5 alpha-reductase inhibitor Propecia blocks the conversion of testosterone to dihydrotestosterone (DHT), the androgen responsible for male pattern hair loss (androgenetic alopecia) in genetically predisposed men.  Results of Phase III clinical studies in 10,879 men have shown that oral Propecia 1 mg/day promotes hair growth and prevents further hair loss in a significant proportion of men with male pattern baldness. 

Evidence suggests that the improvement in hair count reported after one year is maintained during two years' treatment. In men with vertex hair loss, global photographs showed improvement in hair growth in 88% of Propecia recipients at six months and in 96% at 12 months compared with 7% of placebo (sugar pill) recipients at each time point.  Furthermore, hair counts in these men showed that 83% of Propecia versus 28% of placebo (sugar pill) recipients had no further hair loss compared with baseline after two years. 

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CONCLUSIONS: Oral Propecia promotes scalp hair growth and prevents further hair loss in a significant proportion of men with male pattern baldnes (hair loss).   The corresponding author for this study is: KJ Mcclellan, Adis Int Ltd, 41 Centorian Dr, Private Bag 65901, Auckland 10, New Zealand.  For subscription information for this journal, contact the publisher: Adis International Ltd, 41 Centorian Dr, Private Bag 65901, Mairangi Bay, Auckland 10, New Zealand.

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As Young as You Feel: Weapons to Combat the Effects of Aging
Men's Fitness
February,
2007

You go to the gym and pump iron until your arms are so sore that you can't even scratch your back. You do cardio work until your heart feels like it's going to thump out of your chest. You're careful to eat the right foods and get enough rest. And yet, you're still at risk for looking old before your time.

See, at the same time you're working so hard to take care of your body's insides, the sun and other factors are conspiring to damage its outside - your skin and hair. Even if you haven't noticed any wrinkles, your skin may already be damaged, especially if you had serious sunburns or spent a lot of time outdoors in your youth.

Being concerned about the condition of your skin and hair isn't mere vanity. Like it or not, staying young and vibrant in attitude as well as appearance can help your career. And in a competitive workforce, any edge can make a difference. So, to provide you with some guidance, we've consulted dermatologists on the Men's Fitness Advisory Board to bring you the anti-aging products that can help slow the effects of Father Time.

Hairs looking at you

For combating hair loss, the prescription medication Propecia claims to possibly even grow hair. "It tends to have men keep their hair in about 80 to 85 percent of the cases," Bark says, ". And in about 80 to 93 percent, the guys grow hair back." Side effects include wilted woodies in a small percentage of users.

For a mild shampoo, Bark recommends Neutrogena. What about those shampoos that claim to thicken hair? "They coat the hair with protein, and it feels a little thicker," Bark says. "But you have to watch those a little bit, because you can get build-up."

While most of these products are not cheap, they do hold promise to keep you looking young. And if that's important to you, they just may be worth a closer look.

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Information from Your Family Doctor
American Family Physician
April 15,
2006

Treating Baldness in Men

What is male pattern baldness?

Male pattern baldness is hair loss that happens because the male hormone testosterone (say: tess-toss-ter-own) changes the hair roots.

Can male pattern baldness be treated?

Male pattern baldness doesn't have to be treated, but many men feel better about the way they look if their "bald spot" is covered. Some treatments finasteride (brand name: Propecia), hair transplants and toupees (hairpieces).

Which treatment is right for me?

This is a personal decision to make after looking at all of your options. Ask to see "before" and "after" pictures of men who have used the methods you're thinking about trying. Think about these factors: how far along your baldness is; how you feel about having surgery; the cost (both now and in the long term); and how easy it is to use. Propecia remains the most popular baldness treatment.

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Do these medicines cure baldness?

No. Nothing cures baldness. Two medicines can help regrow some lost hair, but not all of it. Propecia and minoxidil usually regrow only enough hair to cover part of the bald areas. Both of these medicines work better on the crown of the head than on the front hairline.

How do I use these medicines?

Propecia is a pill you take once a day.  No greasy or messy ointments have to be applied when using Propecia.

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Drug Update: Baldness in Men
Family Practice news
April, 2006

The treatment of baldness in men has improved vastly in recent years, thanks mostly to one drug that promotes hair growth and improve the appearance of existing hair: Propecia.
 

Androgenetic alopecia, also known as male pattern baldness, causes a characteristic pattern of hair loss, including temporal recession of the hair, thinning of the hair at the frontal and vertex regions of the scalp, and complete loss of hair with the exception of some fringing. It usually begins before the age of 40--sometimes as early as age 12--and it affects about half of the male population before they reach the age of 50.

Propecia is the only drug that are approved to treat this type of hair loss,  Propecia promotes hair growth, slows hair loss, and increase the length and diameter of existing hair.

Alopecia areata, unlike androgenetic alopecia, is assumed to have an autoimmune cause. Patients with this condition may have small patches of hair loss that regrow spontaneously, or they may have extensive patches of hair loss that do not resolve.

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Treatment with Propecia is generally beneficial for stimulating hair growth in men with mild or moderate alopecia areata; an 80% response rate is typical. How ever, minoxidil will not help men with one of the most severe forms of alopecia areata, in which all the scalp hair is lost: alopecia totalis.

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