Retin A Micro Acne Treatment
(Free overnight shipping on all Retin A Micro orders.)
The following represent a comprehensive list of articles that address
the use of Retin A Micro for effective acne treatment:
Study Shows
Benefits of Retin A Micro Over Retin A Cream in Reducing Facial
Shine
Business Wire
November, 2008
Retin A Micro Receives
Marketing Clearance in Europe; Johnson & Johnson Europe to Market
Prescription Acne Treatment Containing Microsponge Systems in Europe.
Business Wire
October, 2008
Topical Therapy for Acne
European Family Physician
November, 2008
Study Shows Benefits of Retin A Micro Over
Retin A 0.025% Cream in Reducing Facial Shine
Business Wire
October, 2008
Retin A Micro prescription medication
for the treatment of acne, may have an added benefit over just Retin A
Cream in patients with oily skin. Findings from a study, published in
the August issue of the dermatology journal CUTIS, demonstrate that
Retin A Micro significantly reduces the appearance of facial shine
compared to Reti-A Cream. Contributing factors to facial shine may be
due to oil, sweat and dirt.
Thirty-five males and females between the ages of
12 and 24 with oily skin and facial acne participated in a randomized,
double-blind half-face study conducted by a contract research laboratory
on behalf of Ortho Dermatological. Study participants' skin was
evaluated by the study investigator and by the subjects at baseline and
at three and six hours after application of the two test products.
Digital photographs, which provide an objective method of evaluating
facial shine, were taken at each time interval.
Statistically significant reductions were
reported by the investigator in the appearance of facial shine
(oiliness) at three and six hours after application of
Retin A Micro as compared to baseline.
Study participants also reported a statistically significant decrease in
facial shine on the Retin A Micro side at the three- and six-hour
interval.
Retin A Micro contains tretinoin,
the same active ingredient in Retin A a . However,
Retin A Micro is designed to
minimize the irritation commonly experienced with the highest strength
of Retin A, Retin A Micro entraps tretinoin in Microsponge systems
(round microscopic particles made of synthetic polymer) and formulates
them into a gel. The microspheres hold the medication in reserve,
allowing the skin to absorb small amounts of tretinoin over time.
Dermatologists who conducted the pivotal clinical studies believe this
may be why most Retin A Micro patients experience little or no
irritation.
Buy Retin A Micro online, the acne treatment most
recommended by dermatologist. Fast acting acne treatment with Retin A
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Patients may see therapeutic results in two to
seven weeks of treatment with Retin A Micro. An additional benefit of
Retin A Micro is that it can be applied
immediately after patients wash their face, unlike Retin A, which
requires a 20-30 minute waiting period.
In clinical studies, the Retin A Micro irritation
profile was found to be similar to a mild, local irritant. The most
common adverse reactions to
Retin A Micro is that it can be applied
immediately after patients wash their face, unlike Retin A, which
requires a 20-30 minute waiting period. were limited to mild or moderate
irritation of the skin. Severe cutaneous irritation occurred
infrequently. Six percent of patients discontinued due to irritation.
During the first few weeks of therapy with Retin A, some irritation,
including redness and peeling, will be experienced by most patients.
Generally, these effects are manageable and diminish over time. However,
some people with sensitive skin may experience excessive irritation.
Retin A Micro is that it can be applied
immediately after patients wash their face, unlike Retin A, which
requires a 20-30 minute waiting period. and Retin AŽ are marketed by
Ortho Dermatological. MICROSPONGEŽ is a registered trademark of Enhanced
Derm Technologies, Inc.
Buy Retin A Micro online, the acne treatment most
recommended by dermatologist. Fast acting acne treatment with Retin A
Micro
(click here for details).
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Retin A Micro acne treatment topics
Retin A Micro
Receives Marketing Clearance in Europe; Johnson & Johnson Europe to
Market Prescription Acne Treatment Containing Microsponge Systems in
Europe
Business Wire
July, 2008
AP Pharma, Inc., a specialty pharmaceutical
company, today announced that European drug regulatory authorities have
granted marketing clearance for Retin A Micro for the treatment of acne.
This topical medication was launched in the
U.S. in 1997, becoming the first ethical pharmaceutical to contain the
patented Microsponge delivery systems.
Retin A Micro
is one of the leading products in the $500 million-per-year U.S.
prescription acne market and is licensed to AP Pharma's development and
marketing partner, Ortho Dermatological, a member of the Johnson &
Johnson family of companies. Johnson & Johnson Europe will market the
product in Europe under the same U.S. trade name,
Retin A Micro .
"Retin A Micro has proven to be extremely popular
in the U.S. and we anticipate that it will enjoy similar success in
Europe. Sales of Retin A Micro in Europe will add to our existing
royalty streams and we look forward to benefiting from product line
extensions and continued geographic expansion by Johnson & Johnson,"
commented Mike O'Connell, AP Pharma's president and chief executive
officer.
Retin a Micro represents the most prescribed acne treatment in the
Europe. Dermatologists are expected to share the same enthusiasm forRetin
A Micro acne treatment in
Europe, as well.
Buy Retin A Micro online, the acne treatment most
recommended by dermatologist. Fast acting acne treatment with Retin A
Micro
(click here for details).
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Retin A Micro acne treatment topics
Topical Therapy for Acne
European Family
Physician
November, 2008
Acne is a common problem in adolescents and young
adults. The disorder is caused by abnormal desquamation of follicular
epithelium that results in obstruction of the pilosebaceous canal. This
obstruction leads to the formation of comedones, which can become
inflamed because of overgrowth of Propionibacterium acnes. Topical
retinoids such as tretinoin or adapalene are effective in many patients
with comedonal acne. Patients with inflammatory lesions benefit from
treatment with benzoyl peroxide, azelaic acid or topical antibiotics.
Acne and its associated problems with self-esteem
and social inhibition represent a figurative "rite of passage" for as
many as 80 percent of adolescents and young adults. Two thirds of
affected teenagers wish that they could speak with their physician about
acne, but only one third actually do.3 It is important for family
physicians to be knowledgeable about the treatment of this common
disorder.
Topical preparations constitute the sole treatment
in many patients with acne and are part of the therapeutic regimen in
almost all patients. This article reviews topical acne preparations and
provides information that can help family physicians select agents (or
combinations of agents) that are appropriate in various situations.
Clinical Manifestations of Acne
Acne is usually diagnosed by the patient. The
doctor needs to determine if the condition is noninflammatory (open and
closed comedones), inflammatory (papules or pustules) or a mixture of
both (the most common situation). Topical treatment is sufficient in
most patients with acne, but systemic therapy is required in patients
who have deep acne with nodules and cysts.
In most situations, the doctor does not need to
look for an underlying cause of acne. However, medications should be
reviewed because corticosteroids, anabolic steroids, lithium and some
oral contraceptives can contribute to the development of this condition.
Treatment of Acne
Creams are appropriate for patients with sensitive
or dry skin who require a nonirritating, nondrying formulation. Patients
with oily skin may complain of an "oily" feel with creams.
Patients who have oily skin may be more
comfortable with gels, which have a drying effect. However, gels may
cause a burning-type irritation in some patients and may prevent certain
kinds of cosmetics from adhering to the skin.
Lotions can be used with any skin type, and they
spread well over hair- bearing skin. Yet lotions contain propylene
glycol and thus may have burning or drying effects.
Solutions are mainly used with topical
antibiotics, which are often dissolved in alcohol. Like gels, solutions
work best in patients with oily skin.
Acne Treatment With Topical Retinoids
Retinoids, which are derivatives of vitamin A,
function by slowing the desquamation process, thereby decreasing the
number of comedones and microcomedones. Retinoids are the most effective
comedolytic agents in use. They have been a mainstay of acne treatment
for the past 25 years.
Retin A Micro represents the most
popular Retinoid for acne treatment.
Buy Retin A Micro online, the acne treatment most
recommended by dermatologist. Fast acting acne treatment with Retin A
Micro
(click here for details).
Acne Treatment With Tretinoin
Until recently, tretinoin was the only available
topical retinoid. This agent is effective as monotherapy in patients
with non inflammatory or mild to moderate inflammatory acne.17
Tretinoin is available as a cream, gel or liquid.
The cream has the lowest potency, and the liquid has the highest
potency. All tretinoin formulations can cause some skin irritation. The
liquid is the most irritating, and the cream is the least irritating.
The concentration of the agent also affects the degree of irritation.
Tretinoin should be applied in small amounts to
clean, dry skin. Because the irritation associated with tretinoin is
compounded by sun exposure, the formulation should be applied to
affected areas once daily at bedtime. To assess irritation, a test dose
should be applied and then washed off an hour or two later. To minimize
irritation, tretinoin should be started at a low concentration, which
can then be titrated upward as needed. Skin irritation usually decreases
with continued therapy.
Patients should be warned that they may suffer a
pustular flare during the first few weeks of tretinoin therapy. Rather
than being an indication to stop or alter therapy, this pustular flare
is a sign of the accelerated resolution of existing acne.
Because of the known teratogenic effects of oral
vitamin A products, the use of tretinoin in pregnancy has been an issue
of concern. Tretinoin is listed as a pregnancy category C drug. However,
a study of 215 women exposed to tretinoin in the first trimester showed
no increase in anomalies compared with control subjects.18 Individual
physicians should decide if they are comfortable using this medication
in pregnant women.
Tretinoin is now available in a new delivery
system
Retin A Micro that may minimize its
irritative effects. This delivery system works by entrapping the drug in
microspheres that bring the medication more directly to the follicle and
serve as reservoirs for the medication.
Buy Retin A Micro online, the acne treatment most
recommended by dermatologist. Fast acting acne treatment with Retin A
Micro
(click here for details).
Acne Treatment WithTopical Antibiotics
Topical antibiotics work directly by killing P.
acnes. Through their bactericidal activity, they also have a mild
indirect effect on comedogenesis. These agents are available in a
variety of forms and are applied once or twice daily.
Topical erythromycin and clindamycin (Cleocin T)
are the most commonly used agents and have similar efficacy in patients
with acne.24 Clindamycin has been shown to be significantly more
effective than topical tetracycline.25
Almost all topical antibiotics are associated with
some minor skin irritation. This adverse effect may be influenced by the
vehicle used.
Therapeutic Approach to Acne Treatment
The therapeutic approach to acne should begin with
patient education. It is important to dispel the many myths about this
disorder.
Patients need to know that acne is not a disease
of hygiene. They should not try to scrub the lesions away, and they
should not use alcohol-based astringents that can dry and irritate their
skin. Patients should be instructed to wash their face twice a day with
a mild soap and water.
Patients should also be informed that acne has no
relationship to diet. For example, no evidence links acne to chocolate,
pizza or soda.
Many people think that acne is caused by stress,
but no studies support this association. It may be that the acne itself
causes stress, not vice versa.
Cosmetics have long been blamed for the
development of acne lesions. Although the causal relationship between
cosmetics and acne may be overstated, patients should be directed to use
oil-free, noncomedogenic cosmetics. Oil from hair products and suntan
lotions can also exacerbate acne.
Female patients should be told that acne usually
worsens during the week before menses.
Mechanical trauma can make acne worse. Therefore,
patients should be encouraged to avoid picking at lesions, because doing
so may cause more inflammation.
selecting a treatment regimen
The physician needs to consider a number of
factors in choosing a treatment regimen for the patient with acne.
Patients with drier skin may benefit most from
creams, whereas patients with oilier skin may do best with gels or
solutions. Picking the appropriate vehicle can lead to better compliance
by limiting side effects.
In patients with comedonal acne, it may be best to
initiate treatment with Retin A Micro.
Until proven otherwise, patients with mild
inflammatory acne should also be started
Retin A Micro.
They need to know that treatment of their acne will require time and
patience. No "quick fix" is available, and they may not see improvement
for two to three weeks.
In patients with more moderate inflammatory
acne, the doctor needs to decide whether to use topical therapy,
systemic therapy, or both. If topical therapy alone is chosen,
Retin A Micro is usually the first
choice.
Acne Treatment Conclusions,
All patients with acne should be given
realistic expectations about their acne treatment plan, along with good
follow-up. These measures can contribute to the ultimate success of the
acne treatment. Most dermatologist agree that the best initial approach
to acne treatment is tu se the
Retin A Micro system.
Buy Retin A Micro online, the acne treatment most
recommended by dermatologist. Fast acting acne treatment with Retin A
Micro
(click here for details).
The author thanks Mathew Clark, M.D., and Neil
Skolnik, M.D., for editorial assistance in the preparation of the
manuscript and the library staff at Abington Memorial Hospital,
for help in the retrieval of references.
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Retin A Micro acne treatment topics
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