Uprima Information Latest Information on Uprima
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Uprima sales are now permitted by the European Commission throughout
Europe. Abbott Laboratories announced that it has received a marketing
authorization from the European Commission for Uprima for the treatment
of impotence. Uprima is the first centrally acting oral
therapy to be approved by the European Commission for the first-line
treatment of impotence. Uprima is a small tablet that dissolves quickly
when placed under the tongue, typically producing an enhanced erection
response in less than 15 minutes.
Uprima's Novel Mode Of Action
For Impotence
Treatment
Since Uprima is administered sublingually (under the tongue),
Uprima enters the bloodstream quickly, bypassing the gastro-intestinal
tract. The rapid absorption of Uprima into the bloodstream allows for
its fast onset of action, typically less than 15 minutes. This makes
Uprima the fastest acting erection enhancement drug..
"Uprima offers several benefits for
patients: Uprima works fast, and Uprima works similarly to the way men
normally have erections," said Professor Jeremy Heaton, of Queen's
University and Kingston General Hospital, Ontario, Canada. "Long-term
data in men who continued in studies demonstrate that Uprima is
successful in more than 90 percent of attempts at intercourse."
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Additional Uprima Impotence Treatment Information
The following Uprima information has been
compiled from a variety of resources in order to give you details
concerning the use of Uprima in promoting fast erection enhancement (impotence
treatment).
What is Uprima?
Uprima (apomorphine) is one of the most recent impotence medications
on the market designed to help men achieve and maintain a sufficient
erection for intercourse.
Uprima represents the fastest acting erection enhancement drug. Some
90 percent of men report enhanced erections within 10 minutes of a
single dose of Uprima.
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Why
is
Uprima
sometimes called apomorphine hcl?
Apomorphine is the generic name for Uprima. The generic name
represents the medications nonproprietary or chemical name, whereas, the
brand name is the name a pharmaceutical give to a medication for
marketing purposes.
How much does Uprima cost?
You can now buy
Uprima online. The following represents our discount Uprima prices.
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What
is the mechanism of action of
Uprima?
Uprima is the first clinically tested sublingual medication to enhance
erections by activating chemicals found in the brain. Uprima tablets are
dissolved under the tongue which stimulate dopamine receptors in the
hypothalamus and mid brain regions.
Subsequently, once sexual stimulation as occurred
an excitatory signal is transmitted via the spinal cord to stimulate
parasympathetic activity in the pelvic region that results in smooth
muscle relaxation in the walls of the arteries supplying the penis. The
relaxation of walls of these arteries allows the arteries to expand so
more blood can flow to the region, hence, improved erections.
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What
is the appropriate dose of Uprima?
Uprima is supplied in 2mg and 3mg tablets individual should take
Uprima at least 30 minutes prior to sexual intercourse. Uprima is most
effective if individuals first consume a glass of water and then place
the tablet under the tongue allowing the medication to dissolve. Most
physicians recommend taking the 2mg tablets first and then increasing
the dose to 3mg if necessary. Individuals should not consume more than
3mg of Uprima in any given eight hour period.
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How long from the
time I dissolve Uprima under my tongue will I start to notice enhanced
erections?
Clinical studies involving
Uprima
have shown:
Some 84% of the
erection enhancement occurred within 10 minutes of dissolving the
Uprima tablet under the tongue 12% of the erections occurred within 14
minutes of dissolving the Uprima tablet under the tongue.
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Will
Uprima
allow me to have an erection for hours?
Once an individual ejaculates his erection will return to the normal
flaccid state. Uprima, however, can shorten the resolution phase or the
time it takes to achieve another erection.
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What
types of results did Uprima produce during clinical trials?
Rome -- Men with impotence who responded to Uprima showed
consistently high rates of success over 18 months, according to data
presented at the 4th Congress of the European Society for Sexual and
Impotence Research (ESSIR).
Across the entire study period, an average of 92
percent of attempts resulted in an enhanced erection firm enough for
intercourse among patients taking UPRIMA 2 mg(1). Efficacy was measured
as the percentage of attempts resulting in an erection firm enough for
intercourse with Uprima, according to patient and partner diary
assessments. Both patient and partner evaluations confirmed the success
rate.
The findings provide important evidence of the
long-term efficacy of Uprima, the first centrally acting oral therapy to
be approved for the first- line treatment of erectile dysfunction.
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What
are the precautions/warnings concerning Uprima?
Individuals who have the following medical conditions should not take
Uprima:
- Cardiovascular complications
i.e. heart attack, congestive heart failure, unstable angina (chest
pain), uncontrolled hypertension or hypotension, history of postural
hypotension, stroke,
- Compromised renal or hepatic
function
- Abnormally formed penis i.e.
angulation, cavernosal fibrosis, Pyronie's disease
- Uprima should not be used in
men where sexual activity is inadvisable
Medications:
Patients taking certain
medications to treat medical conditions i.e. nitrate medications,
certain hypertensive medications, centrally acting dopamine agonist or
antagonists.
Note: Nitrates are found in
many prescription medications used to treat angina (chest pain secondary
to heart disease). Nitrates are also found in recreational drugs.
- Nitroglycerin ( skin patches or
pastes, sprays, ointments and tablets that are used orally)
- Isosorbide mononitrate and
isosorbide dinitrate (tablets that are swallowed, chewed or
dissolved in the mouth)
- Nitrates are found in
recreational drugs i.e. amyl nitrate or nitrate ("poppers").
Individuals who are not sure if any of their medications contain
nitrates should consult with their healthcare professional prior to
using Uprima.
Men who are taking medicines
that contain nitrates (Nitroglycerin) of any kind must never use Uprima.
Patients should not take Uprima even if you only take nitroglycerin
medication occasionally.
Can
I get Uprima over the counter?
No, Uprima should only be taken by prescription from a licensed
doctor. However, Secondary to the advent of the internet you may
now order Uprima online simply by completing an online medical
questionnaire.
Subsequently, a licensed physician will review your medical history and
patient profile. Once approved for a Uprima prescription, your order
shipped discreetly to you.
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